BDBM50314881 CHEMBL1089543::CHEMBL1089873::cis-N-(3-(Guanidinomethyl)benzyl)-N-(4-phenylethylcyclohexyl)-propionamide

SMILES [#6]-[#6]-[#6](=O)-[#6](=[#6]-c1cccc(-[#6]\[#7]=[#6](\[#7])-[#7])c1)-[#6]-1-[#6]-[#6]-[#7](-[#6]-[#6]-c2ccccc2)-[#6]-[#6]-1

InChI Key InChIKey=AUEQSNFWCCJOSI-UHFFFAOYSA-N

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50314881   

TargetKappa-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314881(CHEMBL1089543 | CHEMBL1089873 | cis-N-(3-(Guanidin...)
Affinity DataKi:  162nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314881(CHEMBL1089543 | CHEMBL1089873 | cis-N-(3-(Guanidin...)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314881(CHEMBL1089543 | CHEMBL1089873 | cis-N-(3-(Guanidin...)
Affinity DataKi:  238nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314881(CHEMBL1089543 | CHEMBL1089873 | cis-N-(3-(Guanidin...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314881(CHEMBL1089543 | CHEMBL1089873 | cis-N-(3-(Guanidin...)
Affinity DataIC50: 521nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314881(CHEMBL1089543 | CHEMBL1089873 | cis-N-(3-(Guanidin...)
Affinity DataIC50: 590nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314881(CHEMBL1089543 | CHEMBL1089873 | cis-N-(3-(Guanidin...)
Affinity DataKi:  4.11E+3nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314881(CHEMBL1089543 | CHEMBL1089873 | cis-N-(3-(Guanidin...)
Affinity DataIC50: 4.75E+3nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314881(CHEMBL1089543 | CHEMBL1089873 | cis-N-(3-(Guanidin...)
Affinity DataIC50: 5.82E+3nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314881(CHEMBL1089543 | CHEMBL1089873 | cis-N-(3-(Guanidin...)
Affinity DataKi:  7.80E+3nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed