BDBM50315303 (S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-ylmethyl)-N'-(5,6,7,8-tetrahydro-8-quinolinyl)-1,4-benzenedimethanamine::CHEMBL1093137

SMILES C(NCc1ccccn1)c1ccc(CN(Cc2nc3ccccc3[nH]2)[C@H]2CCCc3cccnc23)cc1

InChI Key InChIKey=YPTODVXKEJXEET-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50315303   

TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: 120nMAssay Description:Inhibition of anti-CXCR4 12G5 monoclonal antibody to CXCR4 in human SUP-T1 cells pretreated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled IL8 from CXCR1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled MIP1beta from CCR5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled IL8 from CXCR2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled MIP1alpha from CCR1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled TARC from CCR4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315303((S)-N-(2-Pyridinylmethyl)-N'-(1H-benzimidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled MCP1 from CCR2b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed