BDBM50315413 5-(3-Phenylfuroxan-4-yloxy)pentylidenebis(phosphonic)-acid::CHEMBL1093434

SMILES O[P+](O)([O-])C(CCCCOc1no[n+]([O-])c1-c1ccccc1)[P+](O)(O)[O-]

InChI Key InChIKey=IWJQOGFLQREZFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315413   

TargetSqualene synthase(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50315413(5-(3-Phenylfuroxan-4-yloxy)pentylidenebis(phosphon...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed