BDBM50315438 4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-indol-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1093445

SMILES COc1ccc2[nH]c(c(\C=C3/Oc4cc(O)cc(O)c4C3=O)c2c1)-c1cccnc1

InChI Key InChIKey=WXXQJPCZRLPSPS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315438   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315438(4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-in...)
Affinity DataIC50: 1nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315438(4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-in...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315438(4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-in...)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed