BDBM50315483 3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)-N-(4-fluorophenylsulfonyl)acrylamide::CHEMBL1090888

SMILES Fc1ccc(cc1)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc3ccccc3c1)C(=O)C2(F)F

InChI Key InChIKey=IQKLMJUDPLRATQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315483   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315483(3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoind...)
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315483(3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoind...)
Affinity DataIC50: 27.2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed