BDBM50315495 3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(3,4-dichlorophenylsulfonyl)acrylamide::CHEMBL1093797

SMILES Clc1ccc(CN2C(=O)Cc3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(Cl)c(Cl)c4)c23)c(Cl)c1

InChI Key InChIKey=IITIDBUPAHYEPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315495   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315495(3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(3,...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315495(3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(3,...)
Affinity DataIC50: 3.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed