BDBM50315503 CHEMBL1092871::N-(3,4-dichlorophenylsulfonyl)-3-(1-(3,4-difluorobenzyl)-2-oxoindolin-7-yl)acrylamide

SMILES Fc1ccc(CN2C(=O)Cc3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(Cl)c(Cl)c4)c23)cc1F

InChI Key InChIKey=PFFVXHDLNGWLIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315503   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315503(N-(3,4-dichlorophenylsulfonyl)-3-(1-(3,4-difluorob...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315503(N-(3,4-dichlorophenylsulfonyl)-3-(1-(3,4-difluorob...)
Affinity DataIC50: 55.4nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed