BDBM50315585 7-Diphenyl-acetylamino-2-(2-furyl)-5-methylthio[1,2,4]-triazolo[1,5-a]-[1,3,5]triazine::CHEMBL1090125

SMILES CSc1nc(NC(=O)C(c2ccccc2)c2ccccc2)n2nc(nc2n1)-c1ccco1

InChI Key InChIKey=YBQYCFLVEKFGGT-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315585   

TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315585(7-Diphenyl-acetylamino-2-(2-furyl)-5-methylthio[1,...)
Affinity DataKi:  170nMAssay Description:Displacement of [125I]-I-AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315585(7-Diphenyl-acetylamino-2-(2-furyl)-5-methylthio[1,...)
Affinity DataKi:  557nMAssay Description:Displacement of [3H]R-PIA from adenosine A1 receptor in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315585(7-Diphenyl-acetylamino-2-(2-furyl)-5-methylthio[1,...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315585(7-Diphenyl-acetylamino-2-(2-furyl)-5-methylthio[1,...)
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed