BDBM50315848 CHEMBL1090568::N-(6-methyl-3-styryl-1H-indazol-5-yl)-2-(thiophen-2-yl)acetamide

SMILES Cc1cc2[nH]nc(\C=C\c3ccccc3)c2cc1NC(=O)Cc1cccs1

InChI Key InChIKey=UDKDYWHGVWVLDY-MDZDMXLPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315848   

TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315848(CHEMBL1090568 | N-(6-methyl-3-styryl-1H-indazol-5-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315848(CHEMBL1090568 | N-(6-methyl-3-styryl-1H-indazol-5-...)
Affinity DataIC50:  47nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed