BDBM50315857 (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(4-methoxyphenylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol::CHEMBL1093910
SMILES COc1ccc(Nc2ncnc3n(cnc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1
InChI Key InChIKey=DHSVZMSVSTXYCS-LSCFUAHRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50315857
Affinity DataKi: 2.30nMAssay Description:Inhibition of binding of 1 nM N6-[3H]cyclohexyladenosine to adenosine A1 receptor on rat cerebral cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [3H]DPCX from human adenosine A1 receptor expressed in CHO cells at high affinity site by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 195nMAssay Description:Displacement of [3H]DPCX from human adenosine A1 receptor expressed in CHO cells by scintillation counting in presence of 10 uM allosteric modulator ...More data for this Ligand-Target Pair
Affinity DataKi: 832nMAssay Description:Displacement of [3H]DPCX from human adenosine A1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.86E+3nMAssay Description:Displacement of [3H]DPCX from human adenosine A1 receptor expressed in CHO cells at low affinity site by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Displacement of [125I]ABA from adenosine A1 receptor of chick cerebellar membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Evaluated for binding affinity against Adenosine A1 receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMAssay Description:Displacement of [3H]-NECA from adenosine A2 receptor of rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO cells assessed as stimulation of ERK1/2 phosphorylationMore data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting in presence of 10...More data for this Ligand-Target Pair
Affinity DataEC50: 123nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Evaluated for binding affinity against Adenosine A1 receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO cells assessed as stimulation of ERK1/2 phosphorylation in presence of 10 uM alloste...More data for this Ligand-Target Pair