BDBM50316256 CHEMBL1094981::isopropyl 4-[6-(4-{[(2-fluoroethyl)carbamoyl]amino}phenyl)-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate
SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc(NC(=O)NCCF)cc1)N1CCOCC1
InChI Key InChIKey=WQJYOLLPRXNMCU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50316256
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ATR by DELFIA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of PI3Kgamma by DELFIA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair