BDBM50316295 CHEMBL1099284::N-(3-Fluorophenyl)-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-sulfonamide hydrochloride

SMILES CN1CCc2[nH]c3ccc(cc3c2C1)S(=O)(=O)Nc1cccc(F)c1

InChI Key InChIKey=RTSLGLYHBXLBEJ-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50316295   

Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50316295(N-(3-Fluorophenyl)-2-methyl-2,3,4,5-tetrahydro-1H-...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human recombinant 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50316295(N-(3-Fluorophenyl)-2-methyl-2,3,4,5-tetrahydro-1H-...)
Affinity DataKi:  7nMAssay Description:Binding affinity to 5HT1A receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50316295(N-(3-Fluorophenyl)-2-methyl-2,3,4,5-tetrahydro-1H-...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production by LANCE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50316295(N-(3-Fluorophenyl)-2-methyl-2,3,4,5-tetrahydro-1H-...)
Affinity DataKi:  39nMAssay Description:Binding affinity to 5HT2C receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50316295(N-(3-Fluorophenyl)-2-methyl-2,3,4,5-tetrahydro-1H-...)
Affinity DataKi:  42nMAssay Description:Binding affinity to 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed