BDBM50316484 CHEMBL1097839::N-[4-(4-{2-[(Dimethylamino)methyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1-ethyl-1H-pyrazol-3-yl)phenyl]-N'-phenylurea

SMILES CCn1cc(-c2ccnc3[nH]c(CN(C)C)cc23)c(-c2ccc(NC(=O)Nc3ccccc3)cc2)n1

InChI Key InChIKey=BTQCPHBDUJMLMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316484   

TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316484BDBM50316484(N-[4-(4-{2-[(Dimethylamino)methyl]-1H-pyrrolo[2,3-...)
Affinity DataIC50: 58nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316484BDBM50316484(N-[4-(4-{2-[(Dimethylamino)methyl]-1H-pyrrolo[2,3-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed