BDBM50317327 CHEMBL1086675::N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide

SMILES CCCc1c(cnn1-c1ccccc1)C(=O)Nc1ccc(Oc2ccnc3cc(sc23)-c2cn(C)cn2)c(F)c1

InChI Key InChIKey=UVABKUWKYDJFPD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317327   

TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317327(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 70nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317327(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 210nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317327(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed