BDBM50317334 CHEMBL1095036::N-(3-fluoro-4-(2-(4-((2-(methylsulfonyl)ethylamino)methyl)phenyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide

SMILES CS(=O)(=O)CCNCc1ccc(cc1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1

InChI Key InChIKey=CIGNUCKEHATOKY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317334   

TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317334(N-(3-fluoro-4-(2-(4-((2-(methylsulfonyl)ethylamino...)
Affinity DataIC50: 60nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317334(N-(3-fluoro-4-(2-(4-((2-(methylsulfonyl)ethylamino...)
Affinity DataIC50: 80nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317334(N-(3-fluoro-4-(2-(4-((2-(methylsulfonyl)ethylamino...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed