BDBM50317677 (4-cyclobutyl-1,4-diazepan-1-yl)((2S,4R)-4-(3-fluorophenoxy)pyrrolidin-2-yl)methanone::CHEMBL1094351

SMILES Fc1cccc(O[C@H]2CN[C@@H](C2)C(=O)N2CCCN(CC2)C2CCC2)c1

InChI Key InChIKey=XAQNCLSQQYEQMI-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317677   

TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50317677((4-cyclobutyl-1,4-diazepan-1-yl)((2S,4R)-4-(3-fluo...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50317677((4-cyclobutyl-1,4-diazepan-1-yl)((2S,4R)-4-(3-fluo...)
Affinity DataKi:  37nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50317677((4-cyclobutyl-1,4-diazepan-1-yl)((2S,4R)-4-(3-fluo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed