BDBM50317703 4-((3S,5R)-5-(4-cyclobutyl-1,4-diazepane-1-carbonyl)pyrrolidin-3-yloxy)benzonitrile::CHEMBL1097881

SMILES O=C([C@H]1C[C@@H](CN1)Oc1ccc(cc1)C#N)N1CCCN(CC1)C1CCC1

InChI Key InChIKey=DCLRBWCBZZADCC-VQTJNVASSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317703   

TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50317703(4-((3S,5R)-5-(4-cyclobutyl-1,4-diazepane-1-carbony...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50317703(4-((3S,5R)-5-(4-cyclobutyl-1,4-diazepane-1-carbony...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of labeled dofetilide human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed