BDBM50317771 2-(4-((1H-benzo[d]imidazol-2-yl)methyl)-1,4-diazepan-1-yl)-N-(4-(trifluoromethyl)phenyl)acetamide::CHEMBL1097701

SMILES FC(F)(F)c1ccc(NC(=O)CN2CCCN(Cc3nc4ccccc4[nH]3)CC2)cc1

InChI Key InChIKey=RYPKEUHHCZTDNT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317771   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50317771(2-(4-((1H-benzo[d]imidazol-2-yl)methyl)-1,4-diazep...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of T-type calcium channel alpha1G expressed in human HEK293 cells assessed as inhibition of peak currents by whole-cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50317771(2-(4-((1H-benzo[d]imidazol-2-yl)methyl)-1,4-diazep...)
Affinity DataIC50:  2.87E+4nMAssay Description:Inhibition of N-type calcium channel alpha1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50317771(2-(4-((1H-benzo[d]imidazol-2-yl)methyl)-1,4-diazep...)
Affinity DataIC50:  4.97E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed