BDBM50317988 CHEMBL1098337::N-(4-amino-4'-fluorobiphenyl-3-yl)benzamide

SMILES Nc1ccc(cc1NC(=O)c1ccccc1)-c1ccc(F)cc1

InChI Key InChIKey=LKRDHRWKHHRCOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317988   

TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317988(N-(4-amino-4'-fluorobiphenyl-3-yl)benzamide | CHEM...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317988(N-(4-amino-4'-fluorobiphenyl-3-yl)benzamide | CHEM...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed