BDBM50318616 4-Imidazol-1-ylmethylxanthen-9-one::CHEMBL1083971

SMILES O=c1c2ccccc2oc2c(Cn3ccnc3)cccc12

InChI Key InChIKey=SWNOXHJBMDOXFE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318616   

TargetCytochrome P450 11B1, mitochondrial(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50318616(4-Imidazol-1-ylmethylxanthen-9-one | CHEMBL1083971)
Affinity DataIC50: 15nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50318616(4-Imidazol-1-ylmethylxanthen-9-one | CHEMBL1083971)
Affinity DataIC50: 17nMAssay Description:Inhibition of aromatase from human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50318616(4-Imidazol-1-ylmethylxanthen-9-one | CHEMBL1083971)
Affinity DataIC50: 44nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate after 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed