BDBM50319051 (2S,3R,4R,5S,6R)-2-(4-chloro-3-((6-methylpyridazin-3-yl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol::CHEMBL1086006::US8541380, 73

SMILES Cc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)nn1

InChI Key InChIKey=SHVDBYHHUFTISK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319051   

TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50319051(US8541380, 73 | CHEMBL1086006 | (2S,3R,4R,5S,6R)-2...)
Affinity DataIC50: 293nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50319051(US8541380, 73 | CHEMBL1086006 | (2S,3R,4R,5S,6R)-2...)
Affinity DataIC50: 293nMAssay Description:Inhibition assay using hSGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2013
Entry Details
US Patent