BDBM50319827 1-(2-(2-(difluoromethoxy)phenyl)-1-(4-fluorophenyl)ethyl)piperazine::CHEMBL1083425

SMILES FC(F)Oc1ccccc1CC(N1CCNCC1)c1ccc(F)cc1

InChI Key InChIKey=IAMMWWXBTYJBCX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319827   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319827(1-(2-(2-(difluoromethoxy)phenyl)-1-(4-fluorophenyl...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319827(1-(2-(2-(difluoromethoxy)phenyl)-1-(4-fluorophenyl...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319827(1-(2-(2-(difluoromethoxy)phenyl)-1-(4-fluorophenyl...)
Affinity DataKi:  1.76E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319827(1-(2-(2-(difluoromethoxy)phenyl)-1-(4-fluorophenyl...)
Affinity DataIC50: 9.12E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed