BDBM50319833 1-(2-(2,3-dihydrobenzofuran-7-yl)-1-phenylethyl)piperazine::CHEMBL1083707

SMILES C(C(N1CCNCC1)c1ccccc1)c1cccc2CCOc12

InChI Key InChIKey=JLTIELDULXFJCW-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319833   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319833(1-(2-(2,3-dihydrobenzofuran-7-yl)-1-phenylethyl)pi...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319833(1-(2-(2,3-dihydrobenzofuran-7-yl)-1-phenylethyl)pi...)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319833(1-(2-(2,3-dihydrobenzofuran-7-yl)-1-phenylethyl)pi...)
Affinity DataKi: >3.16E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319833(1-(2-(2,3-dihydrobenzofuran-7-yl)-1-phenylethyl)pi...)
Affinity DataIC50:  2.14E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed