BDBM50320507 4-[N'-(6-Chloro-7-methyl-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazyno]-3-pyridinesulfonamide::CHEMBL1165822

SMILES Cc1cc2c(SC(NS2(=O)=O)=NNc2ccncc2S(N)(=O)=O)cc1Cl

InChI Key InChIKey=YHRMUQQDTYBGQX-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50320507   

TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320507(4-[N'-(6-Chloro-7-methyl-1,1-dioxo-1,4,2-benzodith...)
Affinity DataKi:  5.80nMAssay Description:Inhibition of human cloned carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320507(4-[N'-(6-Chloro-7-methyl-1,1-dioxo-1,4,2-benzodith...)
Affinity DataKi:  8.10nMAssay Description:Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320507(4-[N'-(6-Chloro-7-methyl-1,1-dioxo-1,4,2-benzodith...)
Affinity DataKi:  46.1nMAssay Description:Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320507(4-[N'-(6-Chloro-7-methyl-1,1-dioxo-1,4,2-benzodith...)
Affinity DataKi:  50.9nMAssay Description:Inhibition of human full length carbonic anhydrase 14 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320507(4-[N'-(6-Chloro-7-methyl-1,1-dioxo-1,4,2-benzodith...)
Affinity DataKi:  101nMAssay Description:Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed