BDBM50320508 4-[N'-(6-Chloro-7-cyano-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide::CHEMBL1165062

SMILES NS(=O)(=O)c1cnccc1NN=C1NS(=O)(=O)c2cc(C#N)c(Cl)cc2S1

InChI Key InChIKey=CECJQYUBCZWVCE-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50320508   

TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320508(4-[N'-(6-Chloro-7-cyano-1,1-dioxo-1,4,2-benzodithi...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320508(4-[N'-(6-Chloro-7-cyano-1,1-dioxo-1,4,2-benzodithi...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of human cloned carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320508(4-[N'-(6-Chloro-7-cyano-1,1-dioxo-1,4,2-benzodithi...)
Affinity DataKi:  78nMAssay Description:Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320508(4-[N'-(6-Chloro-7-cyano-1,1-dioxo-1,4,2-benzodithi...)
Affinity DataKi:  88.3nMAssay Description:Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320508(4-[N'-(6-Chloro-7-cyano-1,1-dioxo-1,4,2-benzodithi...)
Affinity DataKi:  92.3nMAssay Description:Inhibition of human full length carbonic anhydrase 14 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed