BDBM50320509 4-[2-(4-Sulfamoylphenyl)ethylamino]-3-pyridinosulfonamide::CHEMBL1165061

SMILES NS(=O)(=O)c1ccc(CCNc2ccncc2S(N)(=O)=O)cc1

InChI Key InChIKey=NSQHBCSUZOLMBS-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50320509   

TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320509(4-[2-(4-Sulfamoylphenyl)ethylamino]-3-pyridinosulf...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of human cloned carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320509(4-[2-(4-Sulfamoylphenyl)ethylamino]-3-pyridinosulf...)
Affinity DataKi:  15.1nMAssay Description:Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320509(4-[2-(4-Sulfamoylphenyl)ethylamino]-3-pyridinosulf...)
Affinity DataKi:  52nMAssay Description:Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320509(4-[2-(4-Sulfamoylphenyl)ethylamino]-3-pyridinosulf...)
Affinity DataKi:  149nMAssay Description:Inhibition of human full length carbonic anhydrase 14 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50320509(4-[2-(4-Sulfamoylphenyl)ethylamino]-3-pyridinosulf...)
Affinity DataKi:  1.52E+3nMAssay Description:Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed