BDBM50321671 3-(6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-3-yl)benzamide::CHEMBL1170921

SMILES NC(=O)c1cccc(-c2cnc3cnc(-c4cn[nH]c4)cn23)c1

InChI Key InChIKey=QKYNJTSAZMOLFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321671   

TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321671BDBM50321671(3-(6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-3-yl)b...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CHK1 by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321671BDBM50321671(3-(6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-3-yl)b...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of CHK1 (unknown origin) assessed as inhibition of CDC25 phosphorylation after 30 min by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article