BDBM50321675 6-(1H-pyrazol-4-yl)-3-(1H-pyrrol-2-yl)imidazo[1,2-a]pyrazine::CHEMBL1170125

SMILES c1c[nH]c(-c2cnc3cnc(-c4cn[nH]c4)cn23)c1

InChI Key InChIKey=FCNIHLLVHBVUOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321675   

TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321675BDBM50321675(6-(1H-pyrazol-4-yl)-3-(1H-pyrrol-2-yl)imidazo[1,2-...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of CHK1 by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321675BDBM50321675(6-(1H-pyrazol-4-yl)-3-(1H-pyrrol-2-yl)imidazo[1,2-...)
Affinity DataIC50: 2.34E+7nMAssay Description:Inhibition of CHK1 (unknown origin) assessed as inhibition of CDC25 phosphorylation after 30 min by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article