BDBM50321754 (R)-(1-benzyl-6'-methoxy-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran]-2'-yl)methanol::CHEMBL1170965

SMILES CO[C@H]1Cc2sc(CO)cc2C2(CCN(Cc3ccccc3)CC2)O1

InChI Key InChIKey=AQFKRSCFWQXDAD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321754   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50321754((R)-(1-benzyl-6'-methoxy-6',7'-dihydrospiro[piperi...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]-(+)pentazocine from guinea pig brain sigma 1-type opioid receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50321754((R)-(1-benzyl-6'-methoxy-6',7'-dihydrospiro[piperi...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50321754((R)-(1-benzyl-6'-methoxy-6',7'-dihydrospiro[piperi...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed