BDBM50321814 4-((1H-Imidazol-4-yl)methyl)-1-(biphenyl-4-yl)piperidine::CHEMBL1173391

SMILES c1ccc(-c2ccc(N3CCC(Cc4cnc[nH]4)CC3)cc2)cc1

InChI Key InChIKey=YQSXEBUURNJWNA-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321814   

TargetHistamine H3 receptor(Human)
Meiji Seika Kaisha

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321814BDBM50321814(4-((1H-Imidazol-4-yl)methyl)-1-(biphenyl-4-yl)pipe...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Meiji Seika Kaisha

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321814BDBM50321814(4-((1H-Imidazol-4-yl)methyl)-1-(biphenyl-4-yl)pipe...)
Affinity DataIC50: 347nMAssay Description:Antagonist activity at human recombinant histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of RAHM-induced [35S]GTPgammaS bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed