BDBM50321896 (Z)-2,4-Dimethyl-5-[2-oxo-6-(3-p-tolylureido)-1,2-dihydroindol-3-ylidene-methyl]-1H-pyrrole-3-carboxylic acid::CHEMBL1172420

SMILES Cc1[nH]c(\C=C2/C(=O)Nc3cc(NC(=O)Nc4ccc(C)cc4)ccc23)c(C)c1C(O)=O

InChI Key InChIKey=MAQBPYJYNOISMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321896   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321896((Z)-2,4-Dimethyl-5-[2-oxo-6-(3-p-tolylureido)-1,2-...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321896((Z)-2,4-Dimethyl-5-[2-oxo-6-(3-p-tolylureido)-1,2-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321896((Z)-2,4-Dimethyl-5-[2-oxo-6-(3-p-tolylureido)-1,2-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed