BDBM50321905 (Z)-1-(4-Methoxyphenyl)-3-[2-oxo-3-(1H-pyrrol-2-ylmethylene)-2,3-dihydro-1H-indol-6-yl]urea::CHEMBL1173149

SMILES COc1ccc(NC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1

InChI Key InChIKey=NNAMXKXTCQOZGS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321905   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321905((Z)-1-(4-Methoxyphenyl)-3-[2-oxo-3-(1H-pyrrol-2-yl...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321905((Z)-1-(4-Methoxyphenyl)-3-[2-oxo-3-(1H-pyrrol-2-yl...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321905((Z)-1-(4-Methoxyphenyl)-3-[2-oxo-3-(1H-pyrrol-2-yl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321905((Z)-1-(4-Methoxyphenyl)-3-[2-oxo-3-(1H-pyrrol-2-yl...)
Affinity DataIC50: 31nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed