BDBM50321909 (Z)-1-Biphenyl-4-yl-3-[2-oxo-3-(1H-pyrrol-2-ylmethylene)-2,3-dihydro-1H-indol-6-yl]urea::CHEMBL1172837

SMILES O=C(Nc1ccc(cc1)-c1ccccc1)Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1

InChI Key InChIKey=LDRYCDRIKRFDRD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321909   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321909((Z)-1-Biphenyl-4-yl-3-[2-oxo-3-(1H-pyrrol-2-ylmeth...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321909((Z)-1-Biphenyl-4-yl-3-[2-oxo-3-(1H-pyrrol-2-ylmeth...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321909((Z)-1-Biphenyl-4-yl-3-[2-oxo-3-(1H-pyrrol-2-ylmeth...)
Affinity DataIC50: 20nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321909((Z)-1-Biphenyl-4-yl-3-[2-oxo-3-(1H-pyrrol-2-ylmeth...)
Affinity DataIC50: 88nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed