BDBM50322286 CHEMBL1170876::N-[4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]methyl}phenoxy)phenyl]methanesulfonamide hydrochloride

SMILES CCCCN1C(=O)[C@H](CC2CCCCC2)NC(=O)C11CCN(Cc2ccc(Oc3ccc(NS(C)(=O)=O)cc3)cc2)CC1

InChI Key InChIKey=WYOPPQODGSRNAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322286   

TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322286(N-[4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-di...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed