BDBM50322793 4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol::CHEMBL1172779

SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1

InChI Key InChIKey=KOYRCBKCALKGKO-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50322793   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  948nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of human placental CYP19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  7.58E+3nMAssay Description:Inhibition of CYP3A4 expressed in baculovirus infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  948nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of CYP19 in human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  7.58E+3nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed