BDBM50322793 4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol::CHEMBL1172779
SMILES Oc1ccc(cc1O)-c1ccc(Cc2ccncc2)cc1
InChI Key InChIKey=KOYRCBKCALKGKO-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50322793
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
Affinity DataIC50: 948nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of human placental CYP19More data for this Ligand-Target Pair
Affinity DataIC50: 7.58E+3nMAssay Description:Inhibition of CYP3A4 expressed in baculovirus infected insect microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 948nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of CYP19 in human placental microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 7.58E+3nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair