BDBM50323070 4-propyl-6-(4-(trifluoromethoxy)-3-(trifluoromethyl)phenyl)pyrimidine-2-carbonitrile::CHEMBL1209451

SMILES CCCc1cc(nc(n1)C#N)-c1ccc(OC(F)(F)F)c(c1)C(F)(F)F

InChI Key InChIKey=INIJDZXPDCZFFR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50323070   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323070(4-propyl-6-(4-(trifluoromethoxy)-3-(trifluoromethy...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323070(4-propyl-6-(4-(trifluoromethoxy)-3-(trifluoromethy...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323070(4-propyl-6-(4-(trifluoromethoxy)-3-(trifluoromethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323070(4-propyl-6-(4-(trifluoromethoxy)-3-(trifluoromethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed