BDBM50323566 5-((1R,2R)-2-phenylcyclopropyl)pyrimidin-2-amine::CHEMBL1209592

SMILES Nc1ncc(cn1)[C@@H]1C[C@H]1c1ccccc1

InChI Key InChIKey=DQGMJEZOJRTDBE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323566   

TargetMetabotropic glutamate receptor 4(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50323566(5-((1R,2R)-2-phenylcyclopropyl)pyrimidin-2-amine |...)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO-K1 cells assessed as decrease in forskolin-induced intracellular cAMP accumulation af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed