BDBM50323640 CHEMBL1209066::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-(3-(trifluoromethyl)phenyl)quinolin-4-amine

SMILES CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=UZEDLEVQHJATDH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323640   

TargetMAP kinase-activated protein kinase 2(Human)
Astrazeneca R & D Lund

Curated by ChEMBL
LigandPNGBDBM50323640(N-(4-(4-methylpiperazin-1-yl)phenyl)-6-(3-(trifluo...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MK2 assessed as inhibition of [33P]ATP incorporation in to substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed