BDBM50323645 CHEMBL1209120::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-(4-(methylthio)phenyl)quinolin-4-amine

SMILES CSc1ccc(cc1)-c1ccc2nccc(Nc3ccc(cc3)N3CCN(C)CC3)c2c1

InChI Key InChIKey=WKWSSSBOFOOKQN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323645   

TargetMAP kinase-activated protein kinase 2(Human)
Astrazeneca R & D Lund

Curated by ChEMBL
LigandPNGBDBM50323645(N-(4-(4-methylpiperazin-1-yl)phenyl)-6-(4-(methylt...)
Affinity DataIC50: 700nMAssay Description:Inhibition of MK2 assessed as inhibition of [33P]ATP incorporation in to substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed