BDBM50323866 (S)-1-((3R,8R,14S,17S,22aS)-8-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-14-benzyl-17-butyl-4,4,7,7-tetramethyl-1,9,12,15,18-pentaoxoicosahydropyrrolo[2,1-g][1,2,5,8,11,14,17]dithiapentaazacycloicosine-3-carbonyl)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL1214027
SMILES CCCC[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC(C)(C)[C@H](NC(=O)[C@@H]2CCCN2C1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F
InChI Key InChIKey=DKZNWZVQLFXZER-JHOFKJSISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50323866
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]substance P frome rat NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [3H]DPDPE from rat mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at rat mu opioid receptor expressed in mouse HN9.10 cells assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at human opioid delta receptor expressed in mouse HN9.10 cells assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+3nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Displacement of [3H]DPDPE from rat mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Displacement of [3H]substance P frome rat NK2 receptorMore data for this Ligand-Target Pair