BDBM50325020 (+/-)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(3-phenoxyphenyl)imidazolidine-2,4-dione::CHEMBL1222722

SMILES Fc1ccc2CN(CC3(NC(=O)NC3=O)c3cccc(Oc4ccccc4)c3)C(=O)c2c1

InChI Key InChIKey=ZQEAQUSWNZXSRY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325020   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325020((+/-)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-...)
Affinity DataKi:  27nMAssay Description:Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed