BDBM50325213 2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-thiadiazole::CHEMBL1223034
SMILES CC(C)(C)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
InChI Key InChIKey=KBDZMHUBIGWJPD-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50325213
Affinity DataIC50: 2.70nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >20nMAssay Description:Inhibition of CYP2D6 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.54nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Green Cross
Curated by ChEMBL
Green Cross
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG at holding potential of -80 mV to +40 mVMore data for this Ligand-Target Pair
Affinity DataIC50: >20nMAssay Description:Inhibition of CYP3A4 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair