BDBM50326093 (S)-3-((2S,3S)-2-(benzyloxycarbonylamino)-3-methylpentanamido)-5-(phenylsulfonyl)pent-4-enoic acid::CHEMBL1242610

SMILES CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(O)=O)C=CS(=O)(=O)c1ccccc1

InChI Key InChIKey=IEZUTDJHDVXOKT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326093   

TargetCaspase-3(Human)
University of Lisbon

Curated by ChEMBL
LigandPNGBDBM50326093((S)-3-((2S,3S)-2-(benzyloxycarbonylamino)-3-methyl...)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of human recombinant caspase-3 expressed in Saccharomyces cerevisiae CG379 assessed as growth stimulation after 2 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Lisbon

Curated by ChEMBL
LigandPNGBDBM50326093((S)-3-((2S,3S)-2-(benzyloxycarbonylamino)-3-methyl...)
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of human recombinant caspase 3 assessed as fluorescent 7-amido-4-methylcoumarin releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
University of Lisbon

Curated by ChEMBL
LigandPNGBDBM50326093((S)-3-((2S,3S)-2-(benzyloxycarbonylamino)-3-methyl...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant caspase 7 assessed as fluorescent 7-amido-4-methylcoumarin releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed