BDBM50326422 3-(6-(methylamino)imidazo[1,2-b]pyridazin-3-yl)phenol::CHEMBL1240590::US10688093, Compound 437_0284::US11701353, Compound 437_0284

SMILES CNc1ccc2ncc(-c3cccc(O)c3)n2n1

InChI Key InChIKey=MUGLVLYHLQNKGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326422   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50326422(3-(6-(methylamino)imidazo[1,2-b]pyridazin-3-yl)phe...)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of MNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50326422(3-(6-(methylamino)imidazo[1,2-b]pyridazin-3-yl)phe...)
Affinity DataIC50: 2.18E+3nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent