BDBM50328520 CHEMBL1259099::syn-2-Amino-5-oxo-4,7-diphenyl-4,5,7,8-tetrahydropyrano[4,3-b]-pyran-3-carbonitrile

SMILES N=C1OC2=C([C@@H](C1C#N)c1ccccc1)C(=O)O[C@H](C2)c1ccccc1

InChI Key InChIKey=ZTMDIEJJHLGECB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328520   

TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328520(syn-2-Amino-5-oxo-4,7-diphenyl-4,5,7,8-tetrahydrop...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as inhibition of 3[H]-D-Aspartate uptake after 6 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328520(syn-2-Amino-5-oxo-4,7-diphenyl-4,5,7,8-tetrahydrop...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed