BDBM50328522 CHEMBL1259179::N-{(2S)-3-(Biphenyl-4-yl)-1-[(2S)-2-(5-tert-butyl-1H-imidazol-2-yl)pyrrolidin-1-yl]-1-oxopropan-2-yl}-2-hydroxy-2-methylpropanamide

SMILES CC(C)(O)C(=O)N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)N1CCC[C@H]1c1ncc(C(C)(C)C)[nH]1

InChI Key InChIKey=GTLXMWPFDVGKTH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328522   

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50328522BDBM50328522(N-{(2S)-3-(Biphenyl-4-yl)-1-[(2S)-2-(5-tert-butyl-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50328522BDBM50328522(N-{(2S)-3-(Biphenyl-4-yl)-1-[(2S)-2-(5-tert-butyl-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PrCP by FRETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50328522BDBM50328522(N-{(2S)-3-(Biphenyl-4-yl)-1-[(2S)-2-(5-tert-butyl-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50328522BDBM50328522(N-{(2S)-3-(Biphenyl-4-yl)-1-[(2S)-2-(5-tert-butyl-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of mouse PrCP by FRETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed