BDBM50328528 5,6-Dichloro-2-{(2S)-1-[2-methylalanyl-4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-L-phenylalanyl]pyrrolidin-2-yl}-1H-benzimidazole::CHEMBL1259222

SMILES Cn1cc(-c2ccc(C[C@H](NC(=O)C(C)(C)N)C(=O)N3CCC[C@H]3c3nc4cc(Cl)c(Cl)cc4[nH]3)cc2)ccc1=O

InChI Key InChIKey=VHXSUBQZTPVJFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328528   

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50328528BDBM50328528(5,6-Dichloro-2-{(2S)-1-[2-methylalanyl-4-(1-methyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50328528BDBM50328528(5,6-Dichloro-2-{(2S)-1-[2-methylalanyl-4-(1-methyl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human PrCP by FRETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed