BDBM50328530 3-(Biphenyl-4-yl)-1-{2-[5-(3-fluorophenyl)-1H-imidazol-2-yl]-pyrrolidin-1-yl}propan-1-one::CHEMBL1259068

SMILES O=C(CCc1ccc(-c2ccccc2)cc1)N1CCC[C@H]1c1nc(-c2cccc(F)c2)c[nH]1

InChI Key InChIKey=JZKWZHSDMAUSIQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328530   

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50328530BDBM50328530(3-(Biphenyl-4-yl)-1-{2-[5-(3-fluorophenyl)-1H-imid...)
Affinity DataIC50: 158nMAssay Description:Inhibition of human PrCP by FRETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50328530BDBM50328530(3-(Biphenyl-4-yl)-1-{2-[5-(3-fluorophenyl)-1H-imid...)
Affinity DataIC50: 871nMAssay Description:Inhibition of mouse PrCP by FRETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50328530BDBM50328530(3-(Biphenyl-4-yl)-1-{2-[5-(3-fluorophenyl)-1H-imid...)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of human PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed