BDBM50328923 5-chloro-4-(((3R,4S)-N-cyclopropyl-4-(6-((S)-3-(2,6-dichloro-4-methylphenoxy)pyrrolidin-1-yl)pyridin-3-yl)piperidine-3-carboxamido)methyl)-2-(3-methoxypropyl)pyridine 1-oxide::CHEMBL1269761

SMILES COCCCc1cc(CN(C2CC2)C(=O)[C@H]2CNCC[C@@H]2c2ccc(nc2)N2CC[C@@H](C2)Oc2c(Cl)cc(C)cc2Cl)c(Cl)c[n+]1[O-]

InChI Key InChIKey=AFFAQTIQURLOEQ-NHKHRBQYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328923   

TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328923(5-chloro-4-(((3R,4S)-N-cyclopropyl-4-(6-((S)-3-(2,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328923(5-chloro-4-(((3R,4S)-N-cyclopropyl-4-(6-((S)-3-(2,...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed