BDBM50329213 5-(4-chlorophenyl)-N-(3,5-dimethylphenyl)nicotinamide::CHEMBL1271416

SMILES Cc1cc(C)cc(NC(=O)c2cncc(c2)-c2ccc(Cl)cc2)c1

InChI Key InChIKey=RWENXESMVVFVNT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329213   

TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329213(5-(4-chlorophenyl)-N-(3,5-dimethylphenyl)nicotinam...)
Affinity DataIC50:  87nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329213(5-(4-chlorophenyl)-N-(3,5-dimethylphenyl)nicotinam...)
Affinity DataIC50:  610nMAssay Description:Inhibition of mouse NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329213(5-(4-chlorophenyl)-N-(3,5-dimethylphenyl)nicotinam...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed